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Anabolics cycle, steroids without prescriptionThere are no large, long-term, placebocontrolled randomized clinical trials in the ﬁeld of T therapy to provide deﬁnitive conclusions about CV risk. Nonetheless, there exists a rich literature spanning many decades that provides valuable information. As described in more detail subsequently, the 2 recent articles contradict this literature, and on careful review, neither provides credible evidence of increased CV risks. Only 2 additional studies are generally cited as support for that view. In contrast, many dozens of studies, including a modest number of randomized controlled trials (RCTs), indicate that low serum T concentrations are associated with increased CV risk and mortality and that T therapy may have clinically relevant CV beneﬁts.
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