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From Curr Diabetes Rev,146 with permission from Eureka Science LTD. Another study similarly found an inverse relationship between serum T and intimamedia thickness of the thoracic aorta. In a separate study of severely obese hypogonadal men randomized to 54 weeks of diet and exercise alone vs diet and exercise plus T treatment with intramuscular injections of T undecanoate, Ttreated men had significant improvements in cardiac ejection fraction, carotid intima-media thickness, endothelial function, and epicardial fat, the lattermost being associated with CAD. These results suggest a direct contribution of T therapy to CV health in T-deficient men. Carotid intima-media thickness and/or carotid plaque volume are 240 Mayo Clin Proc. IIa Effects of Testosterone Therapy on Fat, Muscle, and Obesity More than 2 dozen RCTs and a similar number of observational studies have consistently revealed that T therapy in T-deficient men results in increased lean and muscle mass, improved strength, decreased total and visceral fat, decreased percent body fat, reduced body mass index, and decreased waist circumference (Table 6). There are no studies documenting increased fat or obesity as a result of T therapy.


The T1 demographics closely match those of the full T1 cohort of 1709 men (data not shown) and the male population of Massachusetts at the time of recruitment. Both follow-up samples had higher proportions of participants 60 and older. Mean (SD) age was 55·2 (8·7), 62·7 (8·3) and 66·6 (7·0) years, and age ranged from 40–70, 48–79 and 55–79 at T1, T2 and T3, respectively. At all three interviews, the majority of men were white, married, employed, and most had at least a high school education, anavar oxandrolone 10mg buy sale, buy anavar 10mg sale oxandrolone. The men in the follow-up samples were less likely to be employed and more likely to be in the top income category than those in the T1 sample.


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